Currently, the most usual analytical methods are established to identify compounds, though analytical methods like gravimetry and titrimetric analysis were the most concern. In the titrimetric analysis method, the endpoint is detected by the colour changes from one medium to another medium (either acidic medium or basic medium) with the addition of substances are known as indicators. Nowadays, many synthetic indicators are available, which produce environmental pollution and are costly. Several synthetic indicators produce toxicity in humans. Therefore, the search for alternative indicators from natural sources is required for cost-effectiveness and to minimize the toxicity and pollutant from the environment.
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