An Overview of Miconia Genus: Chemical Constituents and Biological Activities

Pharmacognosy Reviews,2019,13,26,xx-xx.
Published:October 2019
Type:Review Article
Authors:
Author(s) affiliations:

Gracielle Oliveira Sabbag Cunha1,2, Danielle Coelho da Cruz1, Antônio Carlos Severo Menezes1

1Universidade Estadual de Goiás, Campus de Ciências Exatas e Tecnológicas, Anápolis-GO, BRAZIL.

2Instituto Federal de Educação, Ciência e Tecnologia de Goiás, Campus Anápolis, Anápolis-GO, BRAZIL.

Abstract:

Miconia genus, belonging to Melastomataceae family, is widely distributed in tropical America and includes some native Brazilian species. This paper reviews the literature on this genus, focusing on its chemical constituents and biological activities, in order to build the base for further studies. Of about 1050 species of Miconia, only 21 were studied from a chemical point of view until the present moment. Among these species, 79 different secondary metabolites were isolated, divided into 7 classes: Flavonoids, triterpenes, phenolic acids, steroids, quinones, tannins and lignans. This chemical diversity gives of the genus interesting biological properties, including antimicrobial, antitumor, antioxidant, antidiabetic, trypanocidal, antileishmanial, schistosomicidal, antimalarial, insecticidal, analgesic and anti-inflammatory activities.